The Muscogee, also known as the Muskogee, Muscogee Creek, Creek, Mvskokvlke, or the Muscogee Creek Confederacy are a group of related indigenous peoples of the Southeastern Woodlands. Their original homelands are in what now comprises southern Tennessee, all of Alabama, western Georgia and part of northern Florida.

Like the Cherokee in northeastern Alabama, most of the Muscogee people were forcibly removed by the federal government from their original lands in the 1830s during the Trail of Tears to Indian Territory (now Oklahoma). Some Muscogee fled European encroachment in 1797 and 1804 to establish two small tribal territories in Louisiana and Texas, continued today by their descendants. Another small branch of the Muscogee Creek Confederacy remained in Alabama, and their descendants formed the federally recognized Poarch Band of Creek Indians.